Review




Structured Review

Rotem Industries rotem® delta analyser
Rotem® Delta Analyser, supplied by Rotem Industries, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rotem+delta+analyser/rotem++delta+analyser/pm32114247-0-18-18
Average 90 stars, based on 1 article reviews
rotem® delta analyser - by Bioz Stars, 2026-09
90/100 stars

Images

Related Articles

other:

Article Title: European Society of Veterinary Clinical Pathology (ESVCP)/ European College of Veterinary Clinical Pathology (ECVCP) 20th Annual Meeting Arnhem, Netherlands—September 25‐28, 2019
Article Snippet: European Society of Veterinary Clinical Pathology (ESVCP)/ European College of Veterinary Clinical Pathology (ECVCP) 20th Annual Meeting Arnhem, Netherlands—September 2528, 2019 Oral Platform Presentations: Abstracts 126 Poster Presentations: Abstracts 2760 1 Pretreatment leukocyte ratios as predictors of outcome in canine diffuse large Bcell lymphoma O. Škor1, B. Wolfesberger1, A. Fuchs-Baumgartinger2, K. Řeháková3, K. Škorová3, B. Rütgen2, M. Kleiter1, I. Schwendenwein2 1Department of Companion Animals and Horses; 2Department for Pathobiology, Vetmeduni Vienna, Vienna, Austria; 3Small Animal Clinical Laboratory, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic 2 Siemens’ atellica CH 930 chemistry analyser: Unique optimization for veterinary and pre clinical toxicology laboratories P.J.. O'Brien, M. Garrett Clinical Pathology, University College Dublin, Dublin, Ireland 3 Selective binding to F(AB’)2 and FCfragments by canine antimouse antibodies D. Bergman1, A. Larsson2, H. Hansson-Hamlin1, B. Ström Holst1 1Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden; 2Department of Medical Sciences, Uppsala University, Uppsala, Sweden 4 Acidification of equine urine: Is it required before measurement of ion concentrations?. S. Lapsina, M. Stirn, B. Riond Vetsuisse Faculty, Clinical Laboratory, Zurich, Switzerland 5 Comparison of canine urine specific gravity measurement between various refractometers in a clinical setting K. du Preez, K. Boustead, Y. Rautenbach, A. Goddard, E. Hooijberg Companion Animal Clinical Studies, University of Pretoria, Pretoria, South Africa 6 Correlation between systemic inflammation and urine protein: Creatinine ratio in cats E. Dobson, K. McCallum, T. Williams Department of Veterinary Medicine, University of Cambridge, Cambridge, UK 7 Canine brucellosis in the Netherlands N. Willems1, M. Holtslag2, E. Broens3, M. Tryfonidou1, B. Meij1 1Clinical Sciences of Companion Animals, Utrecht University, Utrecht, The Netherlands; 2Bacteriology and Epidemiology, Wageningen Bioveterinary Research, Lelystad, The Netherlands; 3Veterinary Microbiological Diagnostic Centre, Utrecht University, Utrecht, The Netherlands 8 Oxidative burst and phagocytic activities of phagocytic cells in canine parvoviral enteritis K. du Preez, Y. Rautenbach, E. Hooijberg, A. Goddard Companion Animal Clinical Studies, University of Pretoria, Pretoria, South Africa 9 Prevalence of Cytauxzoon felis in Eastern Kansas, a preliminary report Y. Wikander, K. Reif Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, NY, USA

Article Title: Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial
Article Snippet: Power cuts are common in Nigeria and although back-up power packs were supplied with the ROTEM delta analyser, these also failed on occasions.

Article Title: Reference intervals for thromboelastometry with the ROTEM delta in cats.
Article Snippet: This study aimed to assess precision of viscoelastic measurements of feline blood using the ROTEM® delta analyser and to establish reference intervals.. Intra-assay-variability was evaluated by analysing samples of two cats in quadruplicate.. Reference intervals were established based on 55 clinically healthy European shorthair cats including different sexes and age groups.

Article Title: Pharmacodynamic Effects of a 6-Hour Regimen of Enoxaparin in Patients Undergoing Primary Percutaneous Coronary Intervention (PENNY PCI Study)
Article Snippet: This was performed according to the manufacturer's instructions using a ROTEM delta analyser and in-tem S reagents (Tem Innovations).

FIBTEM Assay:

Article Title: Thromboelastometry as guidance for blood management in patients undergoing cardiac surgery
Article Snippet: KEYWORDS Thromboelastometry; Cardiac surgery; Blood products management; Point-of-care testing The main objective was blood products transfused, and postoperative adverse events and ICU stay were the secondary objectives.. Results: Statistical analysis showed lower transfusion rates of fresh-frozen plasma in group B compared to group A (p < 0.001), as well as red blood cell transfusion during surgery with an average transfusion rate of 3.9 units in group A in comparison to 2.67 units in group B (p = 0.125).. Moreover, fibrinogen infusion was increased in group B compared to group A (p = 0.019).

Coagulation:

Article Title: In-vitro study of species-specific coagulation differences in animals and humans using rotational thromboelastometry (ROTEM).
Article Snippet: Animal tests are conducted in all fields of trauma research, but transferability of these data to humans is limited.. For example, it is still unclear which animal species is most similar to humans in terms of physiology of blood coagulation.. To improve transferability and raise awareness of the existing differences, we compared human coagulation to coagulation of different animals.

Article Title: Reference intervals for rotational thromboelastometry measurements using the ROTEM® delta device in dogs.
Article Snippet: Aims of the present study were to define reference intervals for viscoelastic analyses of canine haemostasis using the ROTEM® delta analyser, and as a secondary aspect to determine the precision (repeatability) of this method.. Blood samples from 125 clinically healthy dogs were included.. Measurements were performed with commercially available activating reagents (ex-tem, in-tem and kaolin solution) as well as without activation.



Similar Products

90
Pentapharm rotem® delta analyser
-hALPCs PCA in <t>ROTEM</t> (Blood). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation was induced in the absence of recalcification. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCs PCA in ROTEM (Plasma). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) obtained from blood incubated in presence or not of cells suspended in human albumin 5%. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCS PCA in ROTEM (no TF addition). Clotting time (CT) essayed by ROTEM after recalcification, without added Tissue Factor (ExTem 20 µL), of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation is induced if absence of recalcification. Hepatocytes (white), hALPCs (black).
Rotem® Delta Analyser, supplied by Pentapharm, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rotem+delta+analyser/rotem++delta+analyser/pmc03416788-155-5-8
Average 90 stars, based on 1 article reviews
rotem® delta analyser - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
TEM International rotem delta analyser
-hALPCs PCA in <t>ROTEM</t> (Blood). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation was induced in the absence of recalcification. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCs PCA in ROTEM (Plasma). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) obtained from blood incubated in presence or not of cells suspended in human albumin 5%. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCS PCA in ROTEM (no TF addition). Clotting time (CT) essayed by ROTEM after recalcification, without added Tissue Factor (ExTem 20 µL), of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation is induced if absence of recalcification. Hepatocytes (white), hALPCs (black).
Rotem Delta Analyser, supplied by TEM International, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rotem+delta+analyser/rotem+delta+analyzers/pm34528253-56-5-8
Average 90 stars, based on 1 article reviews
rotem delta analyser - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
Rotem Industries rotem® delta analyser
-hALPCs PCA in <t>ROTEM</t> (Blood). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation was induced in the absence of recalcification. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCs PCA in ROTEM (Plasma). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) obtained from blood incubated in presence or not of cells suspended in human albumin 5%. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCS PCA in ROTEM (no TF addition). Clotting time (CT) essayed by ROTEM after recalcification, without added Tissue Factor (ExTem 20 µL), of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation is induced if absence of recalcification. Hepatocytes (white), hALPCs (black).
Rotem® Delta Analyser, supplied by Rotem Industries, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rotem+delta+analyser/rotem++delta+analyser/pm32114247-0-18-18
Average 90 stars, based on 1 article reviews
rotem® delta analyser - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
Rotem Industries rotem delta analyser
-hALPCs PCA in <t>ROTEM</t> (Blood). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation was induced in the absence of recalcification. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCs PCA in ROTEM (Plasma). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) obtained from blood incubated in presence or not of cells suspended in human albumin 5%. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCS PCA in ROTEM (no TF addition). Clotting time (CT) essayed by ROTEM after recalcification, without added Tissue Factor (ExTem 20 µL), of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation is induced if absence of recalcification. Hepatocytes (white), hALPCs (black).
Rotem Delta Analyser, supplied by Rotem Industries, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rotem+delta+analyser/rotem++delta+analyser/pm32114247-14-21-21
Average 90 stars, based on 1 article reviews
rotem delta analyser - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
TEM International rotem® delta analyser
-hALPCs PCA in <t>ROTEM</t> (Blood). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation was induced in the absence of recalcification. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCs PCA in ROTEM (Plasma). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) obtained from blood incubated in presence or not of cells suspended in human albumin 5%. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCS PCA in ROTEM (no TF addition). Clotting time (CT) essayed by ROTEM after recalcification, without added Tissue Factor (ExTem 20 µL), of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation is induced if absence of recalcification. Hepatocytes (white), hALPCs (black).
Rotem® Delta Analyser, supplied by TEM International, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rotem+delta+analyser/rotem+delta+analyzers/pm30831006-29-11-14
Average 90 stars, based on 1 article reviews
rotem® delta analyser - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
Rotem Industries rotem-coagulation analyser rotem delta
-hALPCs PCA in <t>ROTEM</t> (Blood). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation was induced in the absence of recalcification. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCs PCA in ROTEM (Plasma). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) obtained from blood incubated in presence or not of cells suspended in human albumin 5%. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCS PCA in ROTEM (no TF addition). Clotting time (CT) essayed by ROTEM after recalcification, without added Tissue Factor (ExTem 20 µL), of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation is induced if absence of recalcification. Hepatocytes (white), hALPCs (black).
Rotem Coagulation Analyser Rotem Delta, supplied by Rotem Industries, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rotem+delta+analyser/rotem++delta+analyser/pmc06329185-56-8-10
Average 90 stars, based on 1 article reviews
rotem-coagulation analyser rotem delta - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results


-hALPCs PCA in ROTEM (Blood). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation was induced in the absence of recalcification. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCs PCA in ROTEM (Plasma). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) obtained from blood incubated in presence or not of cells suspended in human albumin 5%. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCS PCA in ROTEM (no TF addition). Clotting time (CT) essayed by ROTEM after recalcification, without added Tissue Factor (ExTem 20 µL), of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation is induced if absence of recalcification. Hepatocytes (white), hALPCs (black).

Journal: PLoS ONE

Article Title: Bivalirudin in Combination with Heparin to Control Mesenchymal Cell Procoagulant Activity

doi: 10.1371/journal.pone.0042819

Figure Lengend Snippet: -hALPCs PCA in ROTEM (Blood). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation was induced in the absence of recalcification. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCs PCA in ROTEM (Plasma). Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) obtained from blood incubated in presence or not of cells suspended in human albumin 5%. Hepatocytes (white), human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to hALPCs f as compared to control hALPCs vs. hepatocytes vs. control. ***p<0.001 (Kruskal-Wallis test). -hALPCS PCA in ROTEM (no TF addition). Clotting time (CT) essayed by ROTEM after recalcification, without added Tissue Factor (ExTem 20 µL), of citrated whole blood (300 µl) in presence or not of cells suspended in human albumin 5%. No coagulation is induced if absence of recalcification. Hepatocytes (white), hALPCs (black).

Article Snippet: Measurements were performed on a ROTEM® delta analyser (Pentapharm, Munich, Germany).

Techniques: Coagulation, Incubation

Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) with human adult liver progenitor cells (hALPCs), hepatocytes, skin fibroblasts, bone marrow mesenchymal stem cells (BMMSC), bone marrow haematopoietic stem cells (BMHSC), or liver myofibroblasts suspended in human albumin 5% f as compared to control.

Journal: PLoS ONE

Article Title: Bivalirudin in Combination with Heparin to Control Mesenchymal Cell Procoagulant Activity

doi: 10.1371/journal.pone.0042819

Figure Lengend Snippet: Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) with human adult liver progenitor cells (hALPCs), hepatocytes, skin fibroblasts, bone marrow mesenchymal stem cells (BMMSC), bone marrow haematopoietic stem cells (BMHSC), or liver myofibroblasts suspended in human albumin 5% f as compared to control.

Article Snippet: Measurements were performed on a ROTEM® delta analyser (Pentapharm, Munich, Germany).

Techniques: Coagulation

Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) deficient in coagulation factors VII, V, X, and II (7d Pl, 5d Pl, 10d Pl, and 2d Pl, respectively) in presence of cells suspended in human albumin 5%. Human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to normal plasma f as compared to control.

Journal: PLoS ONE

Article Title: Bivalirudin in Combination with Heparin to Control Mesenchymal Cell Procoagulant Activity

doi: 10.1371/journal.pone.0042819

Figure Lengend Snippet: Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of plasma (300 µl) deficient in coagulation factors VII, V, X, and II (7d Pl, 5d Pl, 10d Pl, and 2d Pl, respectively) in presence of cells suspended in human albumin 5%. Human adult liver progenitor cells (hALPCs) (black), control (albumin) (grey). * as compared to normal plasma f as compared to control.

Article Snippet: Measurements were performed on a ROTEM® delta analyser (Pentapharm, Munich, Germany).

Techniques: Coagulation

Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of human adult liver progenitor cells (hALPCs) suspended in human albumin 5% with heparin (Hepar). In contrast, enoxaparin (Eno) or Fondaparinux (Fond) was extemporaneously added to blood in contact with cells suspended in albumin. hALPCs (black), Control (albumin) (grey). * as compared to hALPCs f as compared to control Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of human adult liver progenitor cells (hALPCs) suspended in human albumin 5%. Bivalirudin (Biva) or Hirudin (Hir) was extemporaneously added to blood. hALPCs (black), Control (albumin) (grey). * as compared to hALPCs f as compared to control Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of hepatocytes suspended in human albumin 5% with heparin (Hepar). In contrast, enoxaparin (Eno) or Fondaparinux (Fond) was extemporaneously added to blood in contact with cells suspended in albumin. Hepatocytes (white), Control (albumin) (grey). * as compared to hepatocytes f as compared to control Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) with or without hepatocytes suspended in human albumin 5%. Bivalirudin (Biva) or Hirudin (Hir) was extemporaneously added to blood. Hepatocytes (white), Control (albumin) (grey). * as compared to hepatocytes f as compared to control.

Journal: PLoS ONE

Article Title: Bivalirudin in Combination with Heparin to Control Mesenchymal Cell Procoagulant Activity

doi: 10.1371/journal.pone.0042819

Figure Lengend Snippet: Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of human adult liver progenitor cells (hALPCs) suspended in human albumin 5% with heparin (Hepar). In contrast, enoxaparin (Eno) or Fondaparinux (Fond) was extemporaneously added to blood in contact with cells suspended in albumin. hALPCs (black), Control (albumin) (grey). * as compared to hALPCs f as compared to control Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of human adult liver progenitor cells (hALPCs) suspended in human albumin 5%. Bivalirudin (Biva) or Hirudin (Hir) was extemporaneously added to blood. hALPCs (black), Control (albumin) (grey). * as compared to hALPCs f as compared to control Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of hepatocytes suspended in human albumin 5% with heparin (Hepar). In contrast, enoxaparin (Eno) or Fondaparinux (Fond) was extemporaneously added to blood in contact with cells suspended in albumin. Hepatocytes (white), Control (albumin) (grey). * as compared to hepatocytes f as compared to control Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) with or without hepatocytes suspended in human albumin 5%. Bivalirudin (Biva) or Hirudin (Hir) was extemporaneously added to blood. Hepatocytes (white), Control (albumin) (grey). * as compared to hepatocytes f as compared to control.

Article Snippet: Measurements were performed on a ROTEM® delta analyser (Pentapharm, Munich, Germany).

Techniques: Coagulation

Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of human adult liver progenitor cells (hALPCs) suspended in human albumin 5% with heparin (Hepar), enoxaparin (Eno), or fondaparinux (Fond) extemporaneously added to blood. Combination of anticoagulant drugs was obtained when bivalirudin (Biva) was extemporaneously added to blood. hALPCs (black), Control (albumin) (grey). * as compared to hALPCs f as compared to control $ as compared to bivalirudin Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of hepatocytes suspended in human albumin 5% with heparin (Hepar), enoxaparin (Eno), or fondaparinux (Fond) extemporaneously added to blood. Combination of anticoagulant drugs was obtained when bivalirudin (Biva) was extemporaneously added to blood. Hepatocytes (white), Control (albumin) (grey). * as compared to hepatocytes f as compared to control $ as compared to bivalirudin.

Journal: PLoS ONE

Article Title: Bivalirudin in Combination with Heparin to Control Mesenchymal Cell Procoagulant Activity

doi: 10.1371/journal.pone.0042819

Figure Lengend Snippet: Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of human adult liver progenitor cells (hALPCs) suspended in human albumin 5% with heparin (Hepar), enoxaparin (Eno), or fondaparinux (Fond) extemporaneously added to blood. Combination of anticoagulant drugs was obtained when bivalirudin (Biva) was extemporaneously added to blood. hALPCs (black), Control (albumin) (grey). * as compared to hALPCs f as compared to control $ as compared to bivalirudin Clotting time (CT) assayed by ROTEM after recalcification, with added tissue factor (ExTem 20 µL) of citrated whole blood (300 µl) in presence or not of hepatocytes suspended in human albumin 5% with heparin (Hepar), enoxaparin (Eno), or fondaparinux (Fond) extemporaneously added to blood. Combination of anticoagulant drugs was obtained when bivalirudin (Biva) was extemporaneously added to blood. Hepatocytes (white), Control (albumin) (grey). * as compared to hepatocytes f as compared to control $ as compared to bivalirudin.

Article Snippet: Measurements were performed on a ROTEM® delta analyser (Pentapharm, Munich, Germany).

Techniques: Coagulation